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ey0017.5-6 | Advances in Clinical Practice | ESPEYB17

5.6. Genetic variation in GC and CYP2R1 affects 25-hydroxyvitamin D concentration and skeletal parameters: A genome-wide association study in 24-month-old Finnish children

A Kampe , M Enlund-Cerullo , S Valkama , E Holmlund-Suila , J Rosendahl , H Hauta-Alus , M Pekkinen , S Andersson , O Makitie

To read the full abstract: PLoS Genet. 2019 Dec 16;15(12):e1008530.In brief: This genome-wide association study in a cohort of healthy infants shows that, already during the first two years of life, genetic variation in the genes encoding Vitamin D binding protein and Vitamin D 25-hydroxylase correlate with serum 25(OH)D levels and responses to vitamin D supplementation.<p clas...

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ey0015.5-6 | Towards evidence-based vitamin D supplementation | ESPEYB15

5.6 Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and Infection in Healthy Infants: A Randomized Clinical Trial

J Rosendahl , S Valkama , E Holmlund-Suila , M Enlund-Cerullo , H Hauta-Alus , O Helve , T Hytinantti , E Levälahti , E Kajantie , H Viljakainen , O Mäkitie , S Andersson

To read the full abstract: JAMA Pediatr 2018;172(7):646-654Vitamin D deficiency in infants can lead to impaired bone mineralization and rickets. Since the 1920s, vitamin D has been used to prevent and treat rickets, but the optimal supplementation dose for bone health was unclear. Similarly, potential extra-skeletal benefits of vitamin D in childhood have been inadequately explored. Ac...

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ESPE Yearbook of Paediatric Endocrinology

5.6. Genetic variation in GC and CYP2R1 affects 25-hydroxyvitamin D concentration and skeletal parameters: A genome-wide association study in 24-month-old Finnish children

5.6 Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and Infection in Healthy Infants: A Randomized Clinical Trial

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